Article

Prevalence of the metabolic syndrome in acute myocardial infarction and its impact on hospital outcomes

Department of Biochemistry, BP Koirala Institute of Health Sciences, Dharan, Nepal.
International journal of diabetes in developing countries 04/2009; 29(2):52-5. DOI: 10.4103/0973-3930.53120
Source: PubMed

ABSTRACT To ascertain the prevalence of the metabolic syndrome in patients with acute myocardial infarction; to study the impact of the metabolic syndrome on hospital outcomes; and to find out the association of each component of the metabolic syndrome with acute myocardial infarction (AMI).
Coronary care unit, Department of Medicine, B P Koirala Institute of Health Sciences, Dharan, Nepal.
Hospital-based cross-sectional study.
A total of 84 unselected consecutive patients hospitalized with AMI (diagnosed on the basis of WHO criteria) were categorized according to NCEP ATP III criteria.
Data was analyzed by using the Student's t test and Chi-square test.
Among the 84 AMI patients, 22 (26.19%) fulfilled the criteria for metabolic syndrome. Patients with the metabolic syndrome were older (86% were >50 years of age) and females (27%) were more affected than males (25%). In-hospital case fatality was higher in patients having the metabolic syndrome (5/22) than in those without the syndrome (3/62). Among the five components of the metabolic syndrome, the triglyceride levels had the highest positive predictive value (62%) in AMI; this was followed by fasting blood glucose levels (55%).
The prevalence of the metabolic syndrome is 26.19%; it is associated with high mortality; among its components, the triglyceride level has the highest positive predictive value in AMI patients.

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    ABSTRACT: AIMS: To ascertain the prevalence of the metabolic syndrome in patients with acute myocardial infarction; to study the impact of the metabolic syndrome on hospital outcomes; and to Þ nd out the association of each component of the metabolic syndrome with acute myocardial infarction (AMI). SETTING: Coronary care unit, Department of Medicine, B P Koirala Institute of Health Sciences, Dharan, Nepal. DESIGN: Hospital-based cross-sectional study. MATERIALS AND METHODS: A total of 84 unselected consecutive patients hospitalized with AMI (diagnosed on the basis of WHO criteria) were categorized according to NCEP ATP III criteria. STATISTICAL ANALYSIS: Data was analyzed by using the Student's t test and Chi-square test. RESULTS: Among the 84 AMI patients, 22 (26.19%) fulÞ lled the criteria for metabolic syndrome. Patients with the metabolic syndrome were older (86% were >50 years of age) and females (27%) were more affected than males (25%). In-hospital case fatality was higher in patients having the metabolic syndrome (5/22) than in those without the syndrome (3/62). Among the Þ ve components of the metabolic syndrome, the triglyceride levels had the highest positive predictive value (62%) in AMI; this was followed by fasting blood glucose levels (55%). CONCLUSION: The prevalence of the metabolic syndrome is 26.19%; it is associated with high mortality; among its components, the triglyceride level has the highest positive predictive value in AMI patients.
    International Journal of Diabetes in Developing Countries 04/2009; 29(2):52-5. · 0.37 Impact Factor
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