Synthetic surfaces for human embryonic stem cell culture.

Biomolecular Science and Engineering, University of California, Santa Barbara, CA 93106, USA.
Journal of Biotechnology (Impact Factor: 2.88). 04/2010; 146(3):143-6. DOI: 10.1016/j.jbiotec.2010.01.016
Source: PubMed

ABSTRACT Human embryonic stem cells (hESCs) have numerous potential biomedical applications owing to their unique abilities for self-renewal and pluripotency. Successful clinical application of hESCs and derivatives necessitates the culture of these cells in a fully defined environment. We have developed a novel peptide-based surface that uses a high-affinity cyclic RGD peptide for culture of hESCs under chemically defined conditions.


Available from: Sherry Hikita, Aug 20, 2014
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