Article

Female urethral malignant melanoma with vesical invasion: a case report.

Department of Urology, Vakif Gureba Training and Research Hospital, Istanbul, Turkey.
The Kaohsiung journal of medical sciences (impact factor: 0.61). 02/2010; 26(2):96-8. pp.96-8
Source: PubMed

ABSTRACT We report a 75-year-old female with a primary urethral malignant melanoma. Amass protruding from inside the urethra was detected on physical examination. Abdominopelvic magnetic resonance imaging revealed a mass extending from the urethra with dimensions of 4x2 cm, and periurethral heterogenous fatty planes consistent with infiltration. The histopathologic examination was consistent with HMB45(+) malignant melanoma. We performed cystourethrectomy and bilateral inguinal and pelvic lymphadenectomy in one session. The pathology report revealed primary malignant melanoma of the urethra invading the inferior bladder wall. The patient received no adjuvant therapy because of cardiopulmonary morbidities and the presence of multiple pulmonary metastases. The patient eventually died 13 months after surgery.

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    Article: Primary malignant melanoma of the female urethra.
    Sung Tae Cho, Hyeong Cheol Song, Byungchul Cho, Woo Seok Choi, Won Ki Lee, Yong Seong Lee, Young Goo Lee, Ki Kyung Kim, Sung-Ho Park, Jeong Won Kim
    [show abstract] [hide abstract]
    ABSTRACT: We report here on a rare case of primary malignant melanoma of the female urethra. A 69-year-old female presented at our hospital with a several month history of dysuria, poor stream, gross hematuria, intermittent blood spots, and a painful mass at the external urethral meatus. The physical examination revealed a soft, small, chestnut-sized lesion through the urethral orifice. The mass was tan colored, ulcerated, covered with necrotic tissue, and protruded from the external urethral meatus. The mass was removed by wide local excision under spinal anesthesia. The pathological diagnosis was malignant melanoma of the urethra. Computed tomography of the abdomen as well as a whole-body bone scan showed no evidence of metastasis. The patient has been free of disease for 6 months postoperatively. We discuss the clinicopathologic features and treatment of this tumor.
    Korean journal of urology 03/2012; 53(3):206-8.
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Keywords

75-year-old female
 
Abdominopelvic magnetic resonance imaging
 
adjuvant therapy
 
Amass protruding
 
bilateral inguinal
 
inferior bladder wall
 
multiple pulmonary metastases
 
pathology report
 
periurethral heterogenous fatty planes consistent
 
primary malignant melanoma
 
primary urethral malignant melanoma
 
urethra
 

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