Article

Growth factors, muscle function, and doping.

Department of Surgery, University College Medical School, University of London, London, England, UK.
Endocrinology and metabolism clinics of North America (impact factor: 3.56). 03/2010; 39(1):169-81, xi. DOI:10.1016/j.ecl.2009.11.001 pp.169-81, xi
Source: PubMed

ABSTRACT This article discusses the inevitable use of growth factors for enhancing muscle strength and athletic performance. Much effort has been expended on developing a treatment of muscle wasting associated with a range of diseases and aging. Frailty in the aging population is a major socioeconomic and medical problem. Emerging molecular techniques have made it possible to gain a better understanding of the growth factor genes and how they are activated by physical activity. The ways that misuse of growth factors may be detected and verified in athletes and future challenges for detecting manipulation of signaling pathways are discussed.

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Keywords

aging population
 
article discusses
 
diseases
 
Emerging molecular techniques
 
future challenges
 
growth factor genes
 
growth factors
 
medical problem
 
muscle strength
 
muscle wasting
 
signaling pathways