Article

Genetic diversity and statistical parameters of 15 autosomal STR loci in the Pomeranian subpopulation of Espirito Santo State, Brazil.

Núcleo de Genética Humana e Molecular Departamento de Ciências Biológicas, Centro de Ciências Humanas e Naturais, Universidade Federal do Espírito Santo, Av Marechal Campos, 1468 - Campus de Maruípe, 29040-090 Vitória, ES, Brazil.
Molecular Biology Reports (impact factor: 2.93). 06/2011; 38(5):3013-6. DOI:10.1007/s11033-010-9966-8
Source: PubMed

ABSTRACT Allelic frequencies and other population data analysis are reported for the 15 autosomal Short Tandem Repeats (STR) loci included in the PowerPlex(®)16 kit (CSF1PO, D13S317, D16S539, D18S51, D21S11, D3S1358, D5S818, D7S820, D8S1179, FGA, Penta D, Penta E, TPOX, TH01 and vWA) in Pomeranian's descendants from the Espirito Santo State (ES), Brazil, third largest population of Pomeranian's descendants in the world. They chose the mountain region of the state for their preferred geographic location, and they have a very peculiar lifestyle with a selective mating behavior which has maintained their characteristics as a relatively pure subpopulation. Blood samples were obtained from 82 unrelated volunteers from 11 different cities of Espirito Santo State, where there are the Pomeranian's descendants. All 15 loci analyzed showed Power of Discrimination (PD) values > 0.75. Except the TPOX locus, all analyzed loci were at Hardy-Weinberg equilibrium. This subpopulation has not yet been characterized for STR allelic frequencies used for forensic and genetic identification studies.

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Keywords

15 autosomal Short Tandem Repeats
 
15 loci analyzed
 
82 unrelated volunteers
 
Allelic frequencies
 
analyzed loci
 
Brazil
 
Espirito Santo State
 
FGA
 
forensic
 
genetic identification studies
 
Hardy-Weinberg equilibrium
 
Pomeranian's descendants
 
population data analysis
 
pure subpopulation
 
selective mating behavior
 
STR allelic frequencies
 
subpopulation
 
third largest population
 
TPOX
 
TPOX locus