Article

HBV, HCV co-infection among blood donors in Nigeria.

Indian Journal of Pathology and Microbiology (Impact Factor: 0.68). 01/2010; 53(1):182-3. DOI: 10.4103/0377-4929.59229
Source: PubMed
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    ABSTRACT: Hepatitis B and C have been identified as major causes of Transfusion transmitted infections, in Nigeria. Our objective was to determine the prevalence of HBV and HCV in prospective blood donors in Abeokuta, Nigeria. 305 blood donors were screened for the presence of HBsAg and HCV using a rapid immunochromatographic kit (DiaSpot®). Demographic information information was also collected. Males constituted 96.4%, singles were the majority with 65%. Prevalence of HBsAg was 9.8%, HCV 1.3% and dual positivity 0.3%. Prevalence of HBsAg and HCV among males was 10.2% and 1.4%, while females recorded 0.0% for HCV and HBsAg. Dual positivity was recorded in a male (0.33%). Analysis of the study variables revealed that only educational status was statistically associated with positivity of HBsAg (χ(2) = 7.49, p = 0.02), HCV prevalence was highest in the illiterate group it was not statistically significant (P > 0.05). We report the prevalence rates of anti-HCV Ab and HBsAg in blood donors from Ogun State, Nigeria. Our results reveals higher rate of HBsAg and evidence of co-infection with both viruses, illiteracy was the only variable associated with HBV infection. We advocate for the inclusion of anti-HBc or HBeAg in donor screening in our environment.
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