DSM-IV catatonia signs and criteria in first-episode, drug-naive, psychotic patients: Psychometric validity and response to antipsychotic medication
ABSTRACT To examine the prevalence, psychometric validity and response to antipsychotic drugs of DSM-IV catatonia signs and criteria in patients with a first-episode psychotic disorder.
Two-hundred antipsychotic-naive patients with a DSM-IV nonaffective psychosis were assessed for catatonia signs and criteria using the Modified Rogers Scale, and the psychometric validity of the 12 DSM-IV catatonia signs and diagnostic criteria was examined. Treatment response of catatonia was assessed in 173 patients who completed one-month trial with haloperidol (n=23), risperidone (n=93) or olanzapine (n=57).
Sixty-two patients (31%) endorsed at least one catatonia sign and 24 (12%) met DSM-IV criteria for catatonia. DSM-IV catatonia signs showed an excellent convergent validity (r>0.8) with other rating scales, and DSM-IV criteria showed moderate to fair concordance with other criteria (kappa from 0.57 to 0.77). The total number of signs reflected catatonia severity and demonstrated excellent diagnostic performance against alternative diagnostic criteria. The presence of at least any three signs accurately identified patients with catatonia. Three catatonia domains were identified (hyperkinesia, volitional and hypokinesia), which showed a different association pattern with external variables. Overall, catatonia ratings were particularly related to both dyskinesia and disorganization symptoms and lacked diagnostic specificity for schizophrenia. Patients with catatonia responded well to antipsychotic medication irrespective of the type of antipsychotic drug used, although treatment response was dependent upon the remission of psychotic symptoms.
These results may inform the DSM-V development on diagnosis and classification of catatonia, and indicate that catatonia signs and syndromes are highly responsive to antipsychotic drugs.
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ABSTRACT: Using previously developed models for the bulk and SOI (silicon-on-insulator) MOSFETs, the authors compare and analyze the statistical variation of the threshold voltage V <sub>th</sub> in these MOSFETs with respect to variation of device parameters such as doping density, oxide thickness, and channel length. The statistical variation of the threshold voltage reduction Δ V <sub>th </sub> for three values of channel length is shown. The statistical distribution is broadened with a pronounced asymmetry toward the higher value of Δ V <sub>th</sub>. It is also noted that the statistical distribution in the SOI MOSFET is narrower than that of the bulk MOSFET. The optimized design region of a fully depleted SOI MOSFET with a threshold voltage distribution smaller than its bulk silicon counterpart is shownSOI Conference, 1991. Proceedings, 1991., IEEE International; 11/1991
Article: Dynamic stereo with self-calibration[Show abstract] [Hide abstract]
ABSTRACT: An approach for incremental refinement of disparity maps obtained from a dynamic stereo sequence of a static scene is presented. The approach has been implemented using a binocular stereo vision system mounted on a mobile robot. A robust least median of squares based algorithm is given for recovering the camera motion between successive viewpoints, which provides a self-calibration mechanism. The recovered motion is utilized for recursive disparity prediction and refinement using a robust Kalman filter modelIEEE Transactions on Pattern Analysis and Machine Intelligence 01/1993; 14(12):1184-1189. DOI:10.1109/34.177383 · 5.69 Impact Factor
Conference Paper: Image archive evolution at the University of Florida[Show abstract] [Hide abstract]
ABSTRACT: Studies from the University of Florida indicate that up to 5.7 TeraBytes of uncompressed image data must be stored per year if the radiology department was totally digital. During four years of experience in archiving all clinical CT and MR images, the archive design has been improved to provide reliable and consistent operation. While the acquisition performance has been adequate, initial design deficiencies have limited retrieval performance. An enhanced version of the image archive is currently under development which will substantially increase the capacity and performance for both acquisition and retrievalImage Management and Communications, 1995., Proceedings of the Fourth International Conference on; 09/1995