Article

Triterpenoid from Lycopodium obscurum L.

Laboratory for Natural Product Chemistry, College of Pharmacy, South Central University for Nationalities, Wuhan 430074, China.
Yao xue xue bao = Acta pharmaceutica Sinica 08/2009; 44(8):891-4. pp.891-4
Source: PubMed

ABSTRACT To study the triterpenoid constituents from air-dried whole plants of Lycopodium obscurum L., the constituents were isolated by normal-phase and reverse-phase silica gel column chromatorgraphy from the EtOAc extract. Their structures were elucidated on the basis of spectral analysis. Five triterpenoids were purified and identified as 3beta, 19alpha-dihydroxy-20beta-acetate-serrat-14-en-21beta-ol (1), serratenediol (2), alpha-onocerin (3), 26-nor-8-oxo-alpha-onocerin (4), (3beta, 8beta, 14alpha, 21alpha)-26, 27-dinoronocerane-3, 8, 14, 21-tetrol (5). Compound 1 is a new serratane-type triterpene and compound 5 is isolated from this plant for the first time.

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Keywords

21-tetrol
 
3beta
 
8beta
 
air-dried whole plants
 
EtOAc
 
Lycopodium obscurum L
 
new serratane-type triterpene
 
reverse-phase silica gel column chromatorgraphy
 
serratenediol
 
spectral analysis
 
structures
 
triterpenoid constituents
 
triterpenoids