Sequence types and antimicrobial susceptibility of invasive Streptococcus pneumoniae isolates from a region with high antibiotic selective pressure and suboptimal vaccine coverage

Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
The Pediatric Infectious Disease Journal (Impact Factor: 2.72). 12/2009; 29(5):467-9. DOI: 10.1097/INF.0b013e3181cb45f3
Source: PubMed


Multilocus sequence typing was carried out on 95 invasive pneumococcal isolates belonging to the most common 7 serotypes currently circulating in Taiwan. The study confirmed continued prevalence in Taiwan of a few global clones and sequence types (STs) since the mid-1990s and identified the recent emergence of ST320 (19A) and ST902 (6A). Antimicrobial nonsusceptibility was common in the predominant STs of serotypes 14, 19A, 19F, and 23F.

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