Article

Improved quality of life, clinical, and psychosocial outcomes among heroin-dependent patients on ambulatory buprenorphine maintenance.

Mental Health Services, Ministry of Health, Jerusalem, Israel.
Substance Use &amp Misuse (Impact Factor: 1.23). 01/2010; 45(1-2):288-313. DOI: 10.3109/10826080902873010
Source: PubMed

ABSTRACT A prospective longitudinal design was employed to examine the effects of buprenorphine maintenance on quality of life (QOL), clinical, and psychosocial characteristics of heroin-dependent patients.
Between 2003 and 2005 data were collected on 259 patients attending the outpatient centers for treatment of drug addictions across Israel, of which 157 were reevaluated 16 weeks later and 105 reevaluated 32 weeks later using the Clinical Global Impression, Distress Scale for Adverse Symptoms, Quality of Life Enjoyment and Satisfaction Questionnaire, General Health Questionnaire, General Self-Efficacy Scale, and the Multidimensional Scale of Perceived Social Support. Univariate and multivariate analyses were conducted to examine the association between the parameters and the cross-sectional and longitudinal predictions of the QOL outcomes.
The groups did not differ in baseline values and their post-treatment ratings revealed significant improvement on virtually all the scales. Perceived self-efficacy and social support from friends and significant others at baseline as well as their changes over time were the best predictors of the QOL in the short and long terms. The study's limitations are noted.
The beneficial effects on the QOL were associated with improvement in the psychosocial parameters and a reduction in buprenorphine-related side effects and psychological distress. This study could stimulate research to compare the QOL related to buprenorphine and methadone treatment and serve as a basis on which a controlled study should be performed.

Download full-text

Full-text

Available from: Alexander M. Ponizovsky, Jul 29, 2015
0 Followers
 · 
213 Views
  • Source
    • "Another study used a 16-week and 32-week follow-up to explore changes in quality of life (QoL), clinical, and psychosocial outcomes among heroin-dependent patients who were on ambulatory buprenorphine maintenance [14] . Both follow-up groups revealed significant improvement on virtually all variables studied. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Substance-related disorders are a major public health problem, requiring the development of primary and secondary prevention programs. The Department for the Treatment of Substance Abuse in the Israeli Ministry of Health maintains an administrative database that includes information on all patients enrolled in substitution programs for substance-related disorders. The Israel National Substance Abuse Treatment Registry (INSATR) was introduced in 1996 to ascertain demographic and clinical characteristics of patients, treatment details and legal data that can contribute to the improvement of care coordination, improved population health outcomes and more robust research data for epidemiological, clinical and service policy research. The aim of this report is to describe the INSATR and illustrate its benefits through a review of the findings of INSATR-related clinical trials and linkage studies to other national registries: the National Psychiatric Hospitalization Registry, National Cancer Registry and National AIDS Registry. The INSATR has demonstrated meaningful use in the assessment of quality of care and quality assurance, and in public health service policies research directed to the development of secondary prevention programs for individuals with substance-related problems in the community.
  • [Show abstract] [Hide abstract]
    ABSTRACT: The study set out to examine Quality of Life (QoL), specifically subjective well being in three different addiction populations (260 alcohol-dependent, 282 drug-dependent, and 132 pathological gambling outpatients) at their first visit to treatment, using the Personal Well being Index (PWI). The mean PWI score for all patients was significantly below (i.e., 15 points) Asian norms. Despite reporting a greater addiction severity, alcohol patients scored significantly higher on the PWI compared with drug patients. Despite having demographic characteristics associated with higher functioning, gambling patients did not have the highest QoL; falling in between the alcohol and drug patients. Being married was the only significant predictor of normal personal wellbeing, whilst having debts, a past/current psychiatric morbidity, and a higher addiction severity significantly predicted an abnormal personal wellbeing. Treatment services should pay close attention and target the specific life domains where poor satisfaction is reported by the different addiction populations.
    International Journal of Mental Health and Addiction 01/2012; 10(4). DOI:10.1007/s11469-011-9349-y · 0.95 Impact Factor
  • Source
Show more