Correlates of self-medication for anxiety disorders: results from the National Epidemiolgic Survey on Alcohol and Related Conditions.
ABSTRACT Self-medication is a common behavior among individuals with anxiety disorders, yet few studies have examined the correlates of this behavior. The current study addresses this issue by exploring the pattern of mental health service use and quality of life among people who self-medicate for anxiety. Data came from the National Epidemiologic Survey on Alcohol and Related Conditions and was limited to the subsample of individuals meeting criteria for an anxiety disorder in the past 12 months (n = 4880). Multiple regression analyses compared 3 groups-(1) no self-medication, (2) self-medication with alcohol, and (3) self-medication with drugs, on mental health service use and quality of life. After adjusting for potentially confounding covariates, individuals who engaged in self-medication had significantly higher service use compared with people with anxiety disorders who did not self-medicate (adjusted odds ratio = 1.41, 95% CI = 1.06-1.89). Self-medication was also associated with a lower mental health-related quality of life compared with those who did not self-medicate. Clinicians should recognize and respond to the unique needs of this particular subpopulation of individuals with anxiety disorders.
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ABSTRACT: Social environment influences alcohol consumption in humans; however, animal models have only begun to address biological underpinnings of these effects. We investigated whether social influences on alcohol drinking in the prairie vole are specific to the sex of the social partner. In Experiment 1, control, sham, and gonadectomized voles were placed either in mesh-divided housing with a same-sex sibling or isolation with access to ethanol. In Experiment 2, animals were given an elevated plus maze test (EPM) and then females were paired with a castrated male followed by isolation or mesh-divided housing with access to ethanol. In Experiment 3, subjects categorized as low or high drinkers based on initial ethanol intake were placed in mesh-divided housing with an opposite-sex partner of the same or opposite drinking group and ethanol access. Subjects were then moved back to isolation for a final ethanol access period. Same-sex pairs showed social facilitation of drinking similar to previous reports. Gonadectomy did not affect alcohol drinking. Opposite-sex paired animals in Experiment 2 did not differ in alcohol drinking based on social housing. EPM measures suggested a relationship between anxiety-like behaviors and drinking that depended on social environment. Experiment 3 identified moderate changes in alcohol preference based on social housing, but these effects were influenced by the animal's own drinking behavior and were independent of their partner's drinking. Social influences on alcohol self-administration in prairie voles differ based on the sex of a social partner, consistent with human drinking behavior.Psychopharmacology 08/2012; 224(1):121-32. DOI:10.1007/s00213-012-2836-4 · 3.99 Impact Factor
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ABSTRACT: Alcohol dependence (AD) is more likely to occur among individuals with rather than without an anxiety disorder. Self-medication theory (SMT) holds that drinking behavior is negatively reinforced when alcohol temporarily reduces anxiety and that the resulting escalation of drinking increases the risk for AD. We set out to empirically scrutinize SMT using the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) dataset. We found that only a minority (about 20%) of anxiety disordered individuals endorsed drinking to control anxiety symptoms. This minority drank more alcohol, had a higher cross-sectional rate of AD, and was at higher risk for developing new AD over four years compared to anxiety disordered non-self-medicators and individuals with no anxiety disorder. Consistent with SMT, increased prospective risk for AD among self-medicators is partially mediated by an increased level of alcohol use. Understanding the processes that promote and inhibit self-medication should be a priority for anxiety disorder researchers.Journal of anxiety disorders 10/2010; 25(3):335-9. DOI:10.1016/j.janxdis.2010.10.006 · 2.68 Impact Factor
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ABSTRACT: Self-compassion is a topic of growing research interest and is represented by six facets including self-kindness, self-judgement, mindfulness, over-identification, common humanity and isolation. Recent research interest has begun to examine the use of self-focused compassion and mindfulness as a way of alleviating the distress associated with psychological disorders. Little research exists to examine the relationship between self-compassion, depression, anxiety and stress among individuals who are alcohol-dependent. The present study aimed to address this gap by examining whether high levels of self-compassion will be associated with lower levels of depression, anxiety and alcohol use at entry to treatment. We also examined whether clients whose self-compassion improved over time also reported improvement in depression, anxiety and alcohol use at follow-up. Participants in this study were clients of a publicly funded Drug and Alcohol Service, who completed a baseline and 15-week independent clinical assessment that corresponded with their entry into and exit from treatment with the Service. At baseline, study participants were significantly higher in depression, anxiety, stress, alcohol use, and lower in self-compassion than the general population. At 15 weeks follow-up, participants reported a significant increase in self-compassion, mindfulness, common humanity and self-kindness, and significant decreases in self-judgement, isolation and over-identification. This study provides important preliminary data on self-compassion among a group of people with alcohol dependence.Mindfulness 12/2012; 3(4). DOI:10.1007/s12671-012-0106-5