Population data of 17 Y-STR loci from Rio Grande do Sul state (South Brazil)
ABSTRACT A sample of 255 Brazilian males from Rio Grande do Sul (RS), the Brazilian southernmost state, was typed for 17 Y-STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, YGATA_H4.1 and DYS385ab). A total of 247 haplotypes were identified, of which 239 were unique and eight were found in two individuals each. The haplotype diversity (99.98%) and discrimination capacity (96.86%) were calculated. Pairwise haplotype distances showed that the RS population is not significantly different from Brazil, Rio de Janeiro, and Argentina, is different from São Paulo, Italy, and North Portugal, and is very distant from Spain, the Amazon region, Germany, and South Amerindians. When the RS data was separated in the seven geopolitical regions, some pairs of regions were significantly different; however no region was different from the whole Brazilian sample.
- SourceAvailable from: Sidney Emanuel Batista dos Santos
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- "For this estimation, we used the STR haplotypes of the Macapá population (current study) and the three main parental ethnic groups that formed the Brazilian population: Africans -166 individuals from Angola (Melo et al., 2010), Europeans -175 individuals from Portugal (Pontes et al., 2007) and Native Americans -221 individuals from indigenous tribes in the Brazilian Amazon region (Palha et al., 2010). We also compared the Y haplogroup frequencies estimated from the STR haplotypes of 255 individuals from the State of Rio Grande do Sul in southern Brazil (Schwengber et al., 2009), 200 individuals from the State of São Paulo in southeastern Brazil (Góis et al., 2007), 200 individuals from the city of Belém in the State of Pará, northern Brazil (Palha et al., 2007) and 48 individuals from the city of Brasília, Federal District in central-western Brazil (Grattapaglia et al., 2005). DNA was extracted from peripheral blood mononuclear cells using the phenol-chloroform procedure (Sambrook et al., 1989) and was quantified "
ABSTRACT: The allelic and haplotype frequencies of 17 Y-STR loci most commonly used in forensic testing were estimated in a sample of 138 unrelated healthy males from Macapá, in the northern Amazon region of Brazil. The average gene diversity was 0.6554 ± 0.3315. 134 haplotypes of the 17 loci were observed, 130 of them unique and four present in two individuals each. The haplotype diversity index was 0.9996 + 0.0009, with the most frequent haplogroups being R1b (52.2%), E1b1b (11.6%), J2 (10.1%) and Q (7.2%). Most haplogroups of this population belonged to European male lineages (89.2%), followed by Amerindian (7.2%) and African (3.6%) lineages.Genetics and Molecular Biology 01/2012; 35(1):45-52. DOI:10.1590/S1415-47572011005000061 · 1.20 Impact Factor
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ABSTRACT: This paper builds on previous research from an EA used to predict secondary structure of RNA molecules. The EA predicts which specific canonical base pairs forms hydrogen bonds and helices. Three new thermodynamic models were integrated into our EA. The first based on a modification to our original base pair model. The last two, INN and INN-HB, add stacking-energies using base pair adjacencies. We have tested RNA sequences of lengths 122, 543, and 1494 nucleotides on a wide variety of operators and parameters settings. The accuracy of the predicted structures is compared to the known structures thus demonstrating the benefits of using stacking-energies in structure prediction. Some other improvements to our EA are also discussed.Evolutionary Computation, 2004. CEC2004. Congress on; 07/2004
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ABSTRACT: This paper presents an immune algorithm (IA) based on clonal selection principle using a mutation operator, the hypermacromutation, and an aging process to tackle the protein structure prediction problem (PSP) in the 2D hydrophobic-hydrophilic model. The IA presented has only three parameters. To correctly set these parameters we compute the parameter surfaces, the 3D plots of IA success rate in function of the cloning parameter and the maximum age allowed to each B cell. The parameter surfaces show that hypermacromutation and aging operators are key features for generating diversity and searching more properly the funnel landscape of the PSP problem. Experiments show that the immune algorithm we propose is very competitive with the state-of-art algorithms for the PSP.Evolutionary Computation, 2004. CEC2004. Congress on; 07/2004