Reporting experiments in homeopathic basic research (REHBaR) – A detailed guideline for authors

Karl and Veronica Carstens-Foundation, D-Essen, Germany.
Homeopathy: the journal of the Faculty of Homeopathy (Impact Factor: 0.76). 10/2009; 98(4):287-98. DOI: 10.1016/j.homp.2009.09.006
Source: PubMed


Reporting experiments in basic research in homeopathy is an important issue as comprehensive description of what exactly was done is required. So far, there is no guideline for authors available, unlike criteria catalogues common in clinical research.
A Delphi Process was conducted, including a total of five rounds, three rounds of adjusting and phrasing plus two consensus conferences. European researchers who published experimental work within the last five years were involved.
A checklist of 23 items was obtained and supplemented with detailed examples emphasizing what each item implies. Background, objectives and possible hypotheses should be given in the part 'introduction'. Special emphasis is put on the 'materials and methods' section, where a detailed description of chosen controls, object of investigation, experimental setup, replication, parameters, intervention, allocation, blinding, and statistical methods is required. The section 'results' should present sufficient details on analysed data, descriptive as well as inferential. Authors should discuss their results and give an interpretation in the context of current evidence.
A guideline for Reporting Experiments in Homeopathic Basic Research (REHBaR) was compiled to be applied by authors when preparing their manuscripts, and to be used by scientific journals in the reviewing process. Furthermore the guideline is a commitment to a certain minimum quality level needed in basic research, e.g. blinding and randomisation. Feedback is encouraged on applicability, strength and limitations of the list to enable future revisions.

Download full-text


Available from: Stephan Baumgartner, Oct 09, 2015
118 Reads
  • Source
    • "to develop a test system for examining effects of homeopathic preparations, based on biocrystallograms of extracts of cress seedlings germinating within homeopathic preparations and being extracted with homeopathic preparations, and to report it according to current standards [17]; "
    [Show abstract] [Hide abstract]
    ABSTRACT: A major challenge in basic research into homeopathic potentisation is to develop bioassays that yield consistent results. We evaluated the potential of a seedling-biocrystallisation method. Cress seeds (Lepidium sativum L.) germinated and grew for 4 days in vitro in Stannum metallicum 30x or water 30x in blinded and randomized assignment. 15 experiments were performed at two laboratories. CuCl(2)-biocrystallisation of seedlings extracted in the homeopathic preparations was performed on circular glass plates. Resulting biocrystallograms were analysed by computerized textural image analysis. All texture analysis variables analysed yielded significant results for the homeopathic treatment; thus the texture of the biocrystallograms of homeopathically treated cress exhibited specific characteristics. Two texture analysis variables yielded differences between the internal replicates, most probably due to a processing order effect. There were only minor differences between the results of the two laboratories. The biocrystallisation method seems to be a promising complementary outcome measure for plant bioassays investigating effects of homeopathic preparations.
    Evidence-based Complementary and Alternative Medicine 08/2012; 2012:125945. DOI:10.1155/2012/125945 · 1.88 Impact Factor
  • Source
    • "In preparing the documentation of the experiments, the recommendations for good fundamental research documentation in homeopathy were observed, which were elaborated by the K. and V. Carstens Foundation, Essen [17] "
    [Show abstract] [Hide abstract]
    ABSTRACT: The influence of a homeopathic high dilution of gibberellic acid on wheat growth was studied at different seasons of the year. Seedlings were allowed to develop under standardized conditions for 7 days; plants were harvested and stalk lengths were measured. The data obtained confirm previous findings, that ultrahigh diluted potentized gibberellic acid affects stalk growth. Furthermore, the outcome of the study suggests that experiments utilizing the bioassay presented should best be performed in autumn season. In winter and spring, respectively, no reliable effects were found.
    The Scientific World Journal 09/2011; 11(2):1667-78. DOI:10.1100/2011/462736 · 1.73 Impact Factor
  • Source
    • ". A detailed publication guideline for authors was developed. REHBaR (Reporting experiments in Homeopathic Basic Research) provides a checklist of 23 items, supplemented with detailed examples [4]. Background, objectives and possible hypotheses should be given in the part 'introduction'. "
    [Show abstract] [Hide abstract]
    ABSTRACT: Background: Specific efficacy of homeopathically prepared substances in high dilution levels is controversial due to the comparably low number of randomized controlled clinical trials and due to the low concentrations of the substances potentised. No generally accepted theoretical model is currently available to explain specific effects of such preparations. In order to unequivocally demonstrate any such effects, experimental research has to meet very high standards. Aims: Objective was to compile guidelines for homeopathic basic research regarding experimental design, implementation, execution, evaluation and publication.
Show more