Conference Proceeding

Cooperativity in DNA object self assembly

Dept. of Chem., Marshall Univ., Huntington, WV, USA;
02/2002; DOI:10.1109/NANO.2002.1032249 ISBN: 0-7803-7538-6 pp.291- 294 In proceeding of: Nanotechnology, 2002. IEEE-NANO 2002. Proceedings of the 2002 2nd IEEE Conference on
Source: IEEE Xplore

ABSTRACT Two methods, UV-visible absorption spectroscopy and fluorescence spectroscopy, were used to monitor the initial steps in self assembly of DNA block structures which fuse to form two dimensional nanoarrays. The model system studied consisted of three strands of DNA, two non-interacting strands, and a crossover strand which crosslinks the other two strands. Assembly of this system appears to progress stepwise. Comparison of the assembly temperatures with theory indicates that disjoint sequences may display limited cooperativity.

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Keywords

assembly temperatures
 
crossover strand
 
disjoint sequences
 
initial steps
 
model system
 
non-interacting strands
 
progress stepwise
 
self assembly
 
strands
 
two strands
 

M. Norton