Refractive surgery in patients with retinitis pigmentosa.
ABSTRACT To evaluate the refractive outcomes and safety of laser refractive surgery in a group of myopic patients with retinitis pigmentosa (RP).
This was a multicenter, retrospective, noncomparative, interventional case series. A total of 32 eyes of 16 patients with RP with at least 18 months of follow-up were treated with laser refractive surgery (photorefractive keratectomy [PRK], laser subepithelial keratectomy [LASEK]). Refractive outcomes, complete eye examination, corneal topography, and retinal sensitivities were evaluated during follow-up. Mean follow-up was 28.3 months (minimum 18, maximum 50). Mean patient age was 29.6 years (range 24-54). Mean best-corrected visual acuity (BCVA) was 0.75 preoperatively.
Eighteen months after surgery, mean uncorrected visual acuity (UCVA) was 0.8+/-1 line (p=0.02); mean BCVA was 0.85+/-1 line (p<0.0005) with mean spherical equivalent of -0.16 D. Corneal complications were not detected during follow-up; corneal topography did not show corneal ectasia in any patient after surgery. During follow-up visits, no development or progress of macular edema was noted in any eye. Retinal sensitivities increased after surgery; there were no significant changes in electroretinogram amplitude.
Mean UCVA and BCVA 18 months after surgery were higher than preoperative BCVA. All patients were safely treated without any significant complications. Our results support the safety of performing PRK and LASEK in patients with tapetoretinal degeneration.
Article: Visual acuity measurements.Journal of Cataract and Refractive Surgery 03/2004; 30(2):287-90. DOI:10.1016/j.jcrs.2004.01.014 · 2.55 Impact Factor
International Ophthalmology Clinics 02/2006; 46(3):13-25. DOI:10.1097/00004397-200604630-00004
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ABSTRACT: A 27-year-old man had excimer photoastigmatic keratectomy in the right eye and laser in situ keratomileusis in the left eye for the treatment of equivalent myopia. Preoperative slitlamp examination did not reveal evidence of keratoconus, central corneal pachymetry was 485 microm in the right eye and 500 microm in the left eye, and corneal topography revealed asymmetric bow-tie astigmatism with inferior steepening in the right eye and a small area of inferior steepening in the left eye. Twenty-two months after surgery, the patient complained of poor vision in the left eye. Slitlamp examination of the left eye revealed central corneal thinning and protrusion, with a Fleischer ring within the flap. Corneal topographic evaluation revealed a stable map in the right eye and central corneal steepening indicative of keratectasia in the left eye.Journal of Cataract and Refractive Surgery 01/2005; 30(12):2623-8. DOI:10.1016/j.jcrs.2004.09.037 · 2.55 Impact Factor