Article

Follicular fluid high density lipoprotein-associated micronutrient levels are associated with embryo fragmentation during IVF

Department of Biotechnical and Clinical Laboratory Sciences, University at Buffalo, State University of New York, 26 Cary Hall, 3435 Main Street, Buffalo, NY 14214, USA.
Journal of Assisted Reproduction and Genetics (Impact Factor: 1.77). 11/2009; 26(11-12):557-60. DOI: 10.1007/s10815-009-9367-x
Source: PubMed

ABSTRACT To investigate whether follicular fluid lipid-soluble micronutrients are associated with embryo morphology parameters during IVF.
Follicle fluid and oocytes were obtained prospectively from 81 women. Embryo morphology parameters were used as surrogate markers of oocyte health. HDL lipids and lipid-soluble micronutrients were analyzed by high-pressure liquid chromatography. Non-parametric bi-variate analysis and multivariable ordinal logistic regression models were employed to examine associations between biochemical and embryo morphology parameters.
Follicular fluid HDL cholesterol (r = -0.47, p < 0.01), alpha-tocopherol (r = -0.41, p < 0.01), delta-tocopherol (r = -0.38, p < 0.05) and beta-cryptoxanthine (r = -0.42, p < 0.01) are negatively correlated with embryo fragmentation. Ordinal logistic regression models indicate that a 0.1 mumol/L increase in beta-cryptoxanthine, adjusted for gamma-tocopherol, is associated with a 75% decrease in the cumulative odds of higher embryo fragmentation (p = 0.010).
Follicular fluid HDL micronutrients may play an important role in the development of the human oocyte as evident by embryo fragmentation during IVF.

Download full-text

Full-text

Available from: Michael S Bloom, Jul 28, 2015
0 Followers
 · 
100 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: In this paper we will focus on the use of artificial neural networks (ANNs) for the prediction of stock return volatilities. This stock return volatility is an important and unknown parameter in the Black and Scholes formulas (1973) for the calculation of the value of stock options. We will demonstrate that it is feasible to implement a NARMAX-like structure with neural networks, and to use this architecture for predicting the stock return volatility
    Neural Networks, 1996., IEEE International Conference on; 07/1996
  • [Show abstract] [Hide abstract]
    ABSTRACT: Today, in the network environment, multichannel network meetings are usually implemented by the way of the president-mechanism. Owing to the demand of more and more persons for speech conference in the Internet the author put forward a novel kind of conference-mechanism that can make discussions and withdraw at random. According to the patent algorithm of speech-mixing which our institute has researched and implemented by ourselves the sample interleaving algorithm, in a LAN, real time speech from the multichannel successes in mixing in a normal sound-card building a better base on the discussing conference.
    Signal Processing, 2004. Proceedings. ICSP '04. 2004 7th International Conference on; 01/2004
  • [Show abstract] [Hide abstract]
    ABSTRACT: Sn-doped InP is being used as a platform for a wide variety of fiber communications components, including lasers, LEDs, semiconductor optical amplifiers, modulators and photo-detectors. The more the diameter is, the more imperfection of the InP crystal would be. The substrates with large diameter are desired in order to realize low devices cost. In recent years, we have developed a high quality 3-inch and 4-inch Sn-doped InP single crystal growth using the HP-LEC method after P-injection direct synthesis polycrystalline. It is found that by carefully adjusting the thermal symmetry of the heating field and by further improving the quality of the polycrystalline, three inch and four inch twin-free Sn-doped InP crystals can be obtained even with a shoulder angle of up to 35°-90°, and defects caused by thermal decomposition appear on the surface of the crystals during pulling. For <111> LEC InP crystals, twin formation can be effectively suppressed by optimization of growth conditions, such as thermal field, doping concentration, etc. However, it is difficult to grow twin-free <100> LEC InP in a similar way. It is observed that the yield of single crystal <100> InP can be increased by controlling the ingot shape of a gradually increased diameter.
    Indium Phosphide and Related Materials, 2004. 16th IPRM. 2004 International Conference on; 07/2004
Show more