Differential temporo-parietal cortical networks that support relational and item-based recency judgments.
ABSTRACT There is a growing interest in the parietal cortical role for episodic memory retrieval. Previous functional magnetic resonance imaging (fMRI) studies of recency judgments, judgments of the relative temporal order of two studied items, have highlighted the involvement of the lateral prefrontal and medial temporal regions. However, the parietal cortical contribution to recency judgments has rarely been highlighted. To examine the parietal involvement, in this study, we conducted a re-analysis to increase the statistical power using three data sets (N=73) from our previous fMRI studies of recency judgments. Recency judgments can be achieved by at least two mechanisms, relational and item-based ones. It has been revealed that the left hippocampus/parahippocampal region is related to relational recency judgments, and that the right anterior temporal region is related to item-based recency judgments. We examined whether the parietal cortex is involved in these two types of recency judgments. Significant brain activity related to relational recency judgments was observed in the left ventral parietal region and, as reported previously, the left parahippocampal region. On the other hand, significant brain activity related to item-based recency judgments was observed in the left dorsal parietal region and, as reported previously, the right anterior temporal region. Furthermore, correlation analyses of resting-state BOLD signals detected significant correlations between the ventral parietal region and the parahippocampal region, as well as between the dorsal parietal region and anterior temporal region. These results suggest that the two temporo-parietal networks differentially contribute to relational and item-based recency judgments.
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ABSTRACT: Recent functional imaging work supports the view that item and relational memory depend upon distinct encoding operations within the medial temporal lobe. Specifically, emerging findings demonstrate that the level of engagement of perirhinal cortex predicts later memory for individual items, whereas the level of hippocampal processing correlates with later relational memory, or recovery of additional episodic details. Furthermore, recent functional magnetic resonance imaging evidence in humans suggests that medial temporal lobe cortical input structures, the perirhinal and posterior parahippocampal cortices, differentially participate in the encoding of objects and their context, providing domain-specific input to the hippocampus. Taken together, these data help to construct a working model of how distinct medial temporal lobe structures participate in episodic memory formation with domain-general relational binding mechanisms supported by the hippocampus and provide emerging evidence for domain-specificity within the perirhinal and parahippocampal cortices.Current Opinion in Neurobiology 01/2007; 16(6):693-700. · 7.34 Impact Factor
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ABSTRACT: Although the parietal lobe is not traditionally thought to support declarative memory, recent event-related fMRI studies of episodic retrieval have consistently revealed a range of memory-related influences on activation in lateral posterior parietal cortex (PPC) and precuneus extending into posterior cingulate and retrosplenial cortex. This article surveys the fMRI literature on PPC activation during remembering, a literature that complements earlier electroencephalography data. We consider these recent memory-related fMRI responses within the context of classical ideas about parietal function that emphasize space-based attention and motor intention. We conclude by proposing three hypotheses concerning how parietal cortex might contribute to memory.Trends in Cognitive Sciences 10/2005; 9(9):445-53. · 16.01 Impact Factor
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ABSTRACT: In 2 experiments, the author explored the relations of remember versus familiar ratings to judgments of frequency (JOFs) and to judgments of recency (JORs). In both cases, remembered items were associated with more accurate memory judgments. In general, familiar items were judged to have occurred less frequently and less recently than remembered items. However, JOFs and JORs associated with familiar items were more accurate than chance. Implications for theories of remember versus familiar ratings, JOFs, and JORs are considered. Some basic findings that constrain these theories are that (a) remember versus familiar ratings were less sensitive than JOF to presentation frequency and less sensitive than JOR to recency and (b) although remember versus familiar ratings are strongly related to both JOF and JOR, as measured by gamma, the relations are far from perfect.Journal of Experimental Psychology Learning Memory and Cognition 12/2001; 27(6):1347-58. · 2.92 Impact Factor