Sleep actigraphy evidence of improved sleep after treatment of allergic rhinitis

Department of Pediatric Allergy and Pulmonology, Celal Bayar University School of Medicine, Manisa, Turkey.
Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology (Impact Factor: 2.6). 10/2009; 103(4):290-4. DOI: 10.1016/S1081-1206(10)60527-3
Source: PubMed


Children with allergic rhinitis (AR) are reported to have disturbed sleep and daytime fatigue due to nasal obstruction.
To evaluate sleep impairment in children with AR using actigraphic evaluation.
Fourteen children aged 7 to 16 years with grass pollen-sensitized seasonal AR were enrolled. They completed the Total 4-Symptom Score (T4SS) scoring system for AR symptom score and the Pittsburgh Sleep Quality Index (PSQI) questionnaire for sleep quality, and they underwent actigraphy for 3 days in the pretreatment period. After topical corticosteroid and antihistaminic treatment for 8 weeks, actigraphy, the T4SS, and the PSQI were repeated. Fourteen healthy children aged 8 to 16 years underwent actigraphy and completed the PSQI questionnaire as controls.
There were no significant age or sex differences between the AR and control groups. Pretreatment PSQI and actigraphy scores were worse in the AR group vs the control group. After treatment, sleep quality improved, and there were no differences in actigraphy and PSQI scores between the 2 groups. Before treatment, the T4SS was significantly correlated with the sleep efficiency, daytime napping episodes, and total nap duration variables of actigraphy (r = -0.53, P = .004; r = 0.43, P = .02; and r = 0.39, P = .04, respectively). The T4SS was correlated with the total PSQI score (r = 0.67, P < .001).
Sleep can be compromised in children with AR. There is a significant correlation of clinical symptom score with the actigraphic and PSQI variables. Therefore, actigraphy may be used as an objective tool to evaluate sleep disturbance in children with AR.

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    • "Recent investigations have confirmed that individuals with OSA have marked nasal inflammatory changes,5,6 suggesting a potential link between OSA and rhinitis. This association is also suggested by the clinical observation that patients with allergic rhinitis have poor sleep quality according to actigraphic and Pittsburgh Sleep Quality Index variables.7 Adults with rhinitis have a higher prevalence of OSA,8 and those with rhinitis and OSA have more daytime sleepiness and lower quality of life according to the Epworth sleepiness scale and the Rhinosinusitis Quality of Life Questionnaire.9 "
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    American Journal of Rhinology and Allergy 03/2014; 28(1):56-61. DOI:10.2500/ajra.2014.28.3994 · 1.81 Impact Factor
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    • "Besides physical complications, pediatric AR is associated with disturbance of sleep, psychosocial problems, decrease in school performance due to absenteeism, learning difficulties and distraction as well as impairment in overall quality of life [5] [6] [7] [8] [9]. Thus, high prevalence and significant morbidity makes AR and its treatment a topic of research interest. "
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