Human metapneumovirus infection in a cohort of young asymptomatic subjects.

Section of Microbiology, Department of Pharmaco-Biology, University of Calabria, Rende (Cosenza), Italy.
The New Microbiologica: official journal of the Italian Society for Medical Virology (SIVIM) (Impact Factor: 1.78). 07/2009; 32(3):297-301.
Source: PubMed


Human metapneumovirus (HMPV) is a recently described cause of respiratory infection. The purpose of this study was to to further the available information on the circulation of HMPV among young asymptomatic subjects. The epidemiology of HMPV was examined in a cohort of 73 university students during a winter season by using polymerase chain reaction. HPMV was detected in 3/73 (4.1%) asymptomatic subjects. Phylogenetic analysis has shown that circulating viruses belonged to different HMPV sublineages. Our findings indicate that asymptomatic carriage of HMPV might be a neglected source of viral transmission in the community.

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Available from: Paola Apostoli, Oct 03, 2015
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    • "Primarily at risk of severe HMPV-related disease are infants, immunocompromised patients and the elderly (Boivin et al., 2002; O'Gorman et al., 2006; Sivaprakasam et al., 2007; van den Hoogen et al., 2004b, 2003; Williams et al., 2005). Infection with HMPV can be both symptomatic and asymptomatic (Bruno et al., 2009). Clinical manifestations of symptomatic HMPV are indistinguishable from those of human respiratory syncytial virus (HRSV) and range from mild upper respiratory tract infection to severe disease requiring hospitalisation. "
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