The gut feeling of Treg cells: IL-10 is the silver lining during colitis

Nature Immunology (Impact Factor: 20). 11/2009; 10(11):1141-3. DOI: 10.1038/ni1109-1141
Source: PubMed

ABSTRACT Regulatory T cells that express the transcription factor Foxp3 are pivotal in suppressing autoimmune responses. A report in this issue describes a key role for interleukin 10 produced by lamina propria macrophages in maintaining Foxp3 expression during inflammatory responses in the intestine.

8 Reads
Show more