Article

Pioglitazone induced reversible pancytopenia.

Endocrinology Department, Fatih University Hospital, 06510 Ankara Turkey.
Experimental and Clinical Endocrinology &amp Diabetes (impact factor: 1.69). 10/2009; 118(2):96-7. DOI:10.1055/s-0029-1234065 pp.96-7
Source: PubMed

ABSTRACT Pioglitazone is used to improve insulin sensitivity in type 2 diabetes. This group of drugs is usually well tolerated; however, their use may be associated with several adverse effects including edema, weight gain, macular edema and heart failure. Herein we report a patient who developed pancytopenia on the 7th day of oral pioglitazone treatment for the control of diabetes mellitus and fully recovered 6 days after the cessation of this drug. To the best of our knowledge this is the first reported case of pancytopenia induced by pioglitazone therapy.

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Keywords

6 days
 
7th day
 
adverse effects
 
cessation
 
edema
 
heart failure
 
insulin sensitivity
 
macular edema
 
oral pioglitazone treatment
 
pancytopenia induced
 
Pioglitazone
 
pioglitazone therapy
 
weight gain
 

F Karakurt