Article

Parallel computing strategies for determining viral capsid structure by cryoelectron microscopy

US Nat. Inst. of Health
IEEE Computational Science and Engineering 05/1998; DOI: 10.1109/99.683745
Source: IEEE Xplore

ABSTRACT To calculate a full 3D structural model of a virus capsid,
researchers analyzed cryoelectron micrographs that contain many randomly
oriented images of the views. The authors use parallel computing
techniques to improve the performance of the computational algorithms
that determine each particle's orientation and generate the 3D model.
This enhanced computational performance allows analysis of many more
particles and a more precise determination of their orientations,
letting researchers study important details of virus capsids at higher
resolutions

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