Estadística para investigadores : introducción al diseño de experimentos, análisis de datos y construcción de modelos / G.E.P. Box, W.G. Hunter, J.S. Hunter ; tr. por Luis Arimany de Pablos, Javier Tort-Martorell Llabres.
[Show abstract][Hide abstract] ABSTRACT: In this paper methodological principies of Doehlert designs are reviewed and an algorithm tor its application in sequential optimization is proposed. This algorithm, using surface response methodology, has been tested with successfull results in a problem of mixture resolution by gas chromatography.
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