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Calidad de vida en pacientes con artritis reumatoide en tratamiento ambulatorio con anti-TNF

Grupo de estudio en Atención Farmacéutica. Sociedad Extremeña de Atención Farmacéutica Especializada (SEAFE)
Farmacia hospitalaria: órgano oficial de expresión científica de la Sociedad Española de Farmacia Hospitalaria, ISSN 1130-6343, Vol. 32, Nº. 3, 2008, pags. 178-181 06/2008; DOI: 10.1016/S1130-6343(08)72837-X
Source: OAI

ABSTRACT Objetivo: Evaluar la calidad de vida en pacientes con artritis reumatoide en tratamiento ambulatorio con anti-TNF (etanercept y adalimumab). Método: Estudio observacional, descriptivo y multicéntrico. Se utilizó un cuestionario específico validado (QOL-RA Scale) en su versión en español, manteniendo la confidencialidad al máximo. Para medir la fiabilidad de los resultados se utilizó el coeficiente alfa de Cronbach. Se ha realizado un análisis descriptivo para comparar los resultados obtenidos con estudios realizados en la población estadounidense y colombiana. Resultados: Se seleccionaron 82 pacientes. Destacó el perfil de ama de casa, casada y con ningún estudio o estudios primarios. La media de años de diagnóstico fue 11,81 ± 7,30 años y la de tratamiento con anti-TNF fue de 1,71 ± 1,03 años. Los resultados para la encuesta fueron: habilidad física 5,42 ± 1,67), dolor 5,10 ± 1,83, vida social 7,08 ± 1,96, apoyo 7,45 ± 2,10), estado de ánimo 6,02 ± 2,03, tensión nerviosa 5,50 ± 2,01, artritis 5,15 ± 1,86), salud 5,50 ± 1,77. Los resultados obtenidos fueron similares a los encontrados en la población estadounidense, aunque destaca una menor puntuación en el ánimo y la tensión nerviosa. Sin embargo, la alta puntuación en lo referente al apoyo y la vida social fue más parecida a la obtenida en la población colombiana. Todos los pacientes consideraron que su calidad de vida había mejorado con la medicación anti-TNF. Conclusiones: La calidad de vida en pacientes con artritis reumatoide es baja, determinada por el dolor y los síntomas depresivos. Los pacientes tienen la percepción de que los anti-TNF han mejorado su calidad de vida.

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