Article

Tumor filodes de mama

Ginecología y obstetricia clínica, ISSN 1695-3827, Vol. 7, Nº. 1, 2006, pags. 16-23 01/2006;
Source: OAI

ABSTRACT El tumor filodes, descrito por primera vez por Müller en el año 1838, es una neoplasia fibroepitelial que histológicamente se asemeja al fibroadenoma. Es una entidad poco frecuente que representa un 0,3-0,9% de los tumores mamarios. A diferencia del fibroadenoma, este tumor presenta una alta incidencia de recurrencias locales tras la cirugía y tiene potencial para metastatizar por vía hematógena. La presentación típica de esta enfermedad es la de una gran tumoración mamaria indolora, bien delimitada y de rápido crecimiento. Por lo general, no puede ser diferenciado de otras lesiones mamarias benignas o malignas por unas determinadas características en mamografía o ecografía. El diagnóstico exacto sólo puede ser realizado en base a criterios anatomopatológicos y hoy todavía existen dificultades en su diagnóstico histológico, clasificación y correlación entre los parámetros clínicos e histopatológicos. Clásicamente se subdividen en formas benignas, bordeline o malignas en función del sobrecrecimiento estromal, la hipercelularidad y el incremento en el número de mitosis. El pilar en el manejo de este tipo de tumores es su resección quirúrgica amplia y completa, siendo el papel de la radioterapia o quimioterapia controvertido por el escaso número de estudios randomizados existentes.

0 Bookmarks
 · 
550 Views
  • [Show abstract] [Hide abstract]
    ABSTRACT: Phyllodes tumor of the breast is a highly uncommon fibroepithelial tumor, representing 0.3 to 0.9% of all breast tumors. The definitive diagnosis is histological and the goal of treatment is wide and complete surgical excision of the tumor with disease-free margins.We report two patients, aged 33 and 38 years old, with phyllodes tumor of the breast diagnosed and treated in our center. We discuss the diagnostic techniques, surgical approaches, and follow-up in these patients and compare our experience with reports in the literature.
    Revue Neurologique - REV NEUROL. 01/2013;
  • [Show abstract] [Hide abstract]
    ABSTRACT: Introduction: Phyllodes Tumor is a very low frequent breast fibroepithelial neoplasm, representing between 0.3 and 0.9 % of breast tumors and around 2.5% of fibroepithelial tumors as a whole. Ap- pears amid 35 and 55 years old. Goal: To present one case of cystosarcoma phyllodes in a postmenopausal, nuliparous woman. Clinical case: Female patient, 54 years old, smoker, postmenopausal, nuliparous, free of family his- tory of breast cancer, whose first complaint is a huge 10x12x7.5 inches bulk located on right breast, multiloculated, renitent to palpation, painless, movable against deeper plane and skin. Negative axilar nodes. After insicional biopsy, the histopathological report is of a high grade mixed pattern sarcoma. The estadification investigation concludes the tumor is locally advanced without metastasis and surgi- cal procedures got set. Results: Radical mastectomy was performed sparing axilar dissection to minimize postoperatory morbimortality. Adjuvant radiotherapy (50 gray) was directed over surgical area. The patient did well, reconstructive mammoplasty (previously expansor device was required) and contralateral adenomas- tectomy were performed after 6 months. In both sides prosthetic implants were left. Conclusion: The therapy must be surgical, the procedure depending on tumor quality and extension as well as breast commorbilities. Lymph node compromise is very infrequent so as elective axilar dis- section is not mandatory.

Full-text

View
23 Downloads
Available from