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¿Es fiable el test del aliento para el diagnóstico de infección por Helicobacter pylori en atención primaria?

Atención Primaria (Impact Factor: 0.96). 01/2003; DOI: 10.1016/S0212-6567(03)79144-6
Source: OAI

ABSTRACT Objetivo. Evaluar la fiabilidad del test del aliento con urea 13C en atención primaria para el diagnóstico de infección por Helicobacter pylori (Hp). Diseño. Estudio descriptivo, prospectivo y multicéntrico. Emplazamiento. Área urbana perteneciente al Centro de Salud Actur Sur de Zaragoza, con participación del Hospital Miguel Servet. Participantes. Se incluyó a 87 pacientes con diagnóstico clínico de dispepsia funcional. A todos ellos se les realizó un test de aliento con urea 13C, así como una gastroscopia con toma de muestras para histología y test de ureasa rápida. Mediciones principales. Se valoraron edad, sexo y la presencia de positividad o negatividad de infección por Hp en la histología, el test de ureasa y el test del aliento, considerando la histología y el test de ureasa pruebas gold standard para esta medición, por lo que se exigía que el resultado en ambas fuera positivo o negativo para considerarlo no equívoco. Resultados. Se excluyeron 2 casos por resultados equívocos. El 77,6% (66/85) fue positivo por histología y test de ureasa, de los que un 92,4% (61/66) resultó positivo al test del aliento. La sensibilidad de esta prueba fue del 92% y la especificidad del 100%. Conclusiones. El test del aliento en atención primaria tiene un alto valor diagnóstico de infección por Hp, pudiendo evitar así en algunos casos la realización de técnicas más invasivas como la gastroscopia.

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Fernando Gomollón