Leiomyosarcoma of femoral vein in an adult.
Department of Surgery, Combined Military Hospital, Rawalpindi.Journal of the College of Physicians and Surgeons--Pakistan: JCPSP (Impact Factor: 0.35). 10/2005; 15(10):656-7.
A middle aged female presented with a swelling in the groin on the left side. On examination, it was an oval mildly tender firm mass, adherent to underlying structures and extending into the pelvis with pulsatility and bruit. It was diagnosed as leiomyosarcoma of femoral vein on fine needle aspiration cytology and selective left common iliac and common femoral angiography of the lesion. En-bloc wide excision of the mass including the femoral vessels was carried out with saphenous vein graft interposition for restoration of vascular continuity for both vessels. Femoral nerve was sacrificed for tissue clearance. The defect was large and led to permanent limp and walk with a support. The lady was followed up for two years. She was found to have no local recurrence or detectable metastases.
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ABSTRACT: Leiomyosarcoma (LMS) is a rare malignant tumor of smooth muscle origin that generally stems from soft tissues and uterine tissue. However, a small percentage of this sarcoma subset may originate from the smooth muscle of vessel walls, most of which are of venous origin. Although the vena cava (VC) serves as the most likely source for these tumors and has been well described in the literature, there is limited information focused on non-VC LMS derived from large veins. The focus of this study was to consolidate the reports and previously published data of all non-VC LMS of venous origin to better characterize and describe this disease process. We reviewed information derived from 143 previously published cases. It was determined that women aged 60-69 years were most commonly diagnosed with this particular type of tumor, with the most common tumor site being the renal vein. Metastasis was present in 12 % of this population at the time of diagnosis, and 32 % of patients were alive 4 years later.Annals of Surgical Oncology 05/2012; 19(11):3368-74. DOI:10.1245/s10434-012-2379-2 · 3.93 Impact Factor
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