Article

Summon SUMO to Wrestle with Inflammation

Division of Hematology-Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Molecular cell (Impact Factor: 14.46). 09/2009; 35(6):731-2. DOI: 10.1016/j.molcel.2009.09.002
Source: PubMed

ABSTRACT In this issue of Molecular Cell, Lee et al. (2009) report that SUMOylation of nuclear receptors LXRalpha and LXRbeta plays a critical role in the transrepression of IFN-gamma-induced STAT1-dependent inflammatory responses in brain astrocytes.

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    ABSTRACT: Received 9 March 2012; Accepted 12 April 2012Academic Editor: Philip Coffino
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    07/2012; 2012:875148. DOI:10.1155/2012/875148