Article

Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, human papillomavirus, and polyomavirus are not detectable in human tissue with epithelial ovarian cancer, borderline tumor, or benign conditions.

Department of Clinical Science/Obstetrics and Gynecology, Umeå University, Sweden.
American journal of obstetrics and gynecology (impact factor: 3.28). 09/2009; 202(1):71.e1-6. DOI:10.1016/j.ajog.2009.07.042 pp.71.e1-6
Source: PubMed

ABSTRACT We sought to analyze the presence of the microorganisms Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, human papillomavirus (HPV), and the polyomaviruses BK virus (BKV) and JC virus (JCV) in ovarian tissues of women with ovarian carcinomas, borderline tumors, and benign conditions.
Ovarian tissue, snap-frozen and stored at -80 degrees C, from 186 women with benign conditions, borderline tumors, and epithelial ovarian cancer, as well as tissue from the contralateral ovary of 126 of these women, were analyzed regarding presence of C trachomatis and N gonorrhoeae (transcription mediated amplification), M genitalium (real-time polymerase chain reaction [PCR]), HPV (PCR), and BKV and JCV (PCR).
All the tissue samples studied were found negative for the microorganisms analyzed.
C trachomatis, M genitalium, N gonorrhoeae, HPV, and the polyomaviruses BKV and JCV are not detectable in ovarian tissues either from women with benign conditions and borderline tumors or from women with ovarian cancer.

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Keywords

-80 degrees C
 
borderline tumors
 
C trachomatis
 
contralateral ovary
 
epithelial ovarian cancer
 
human papillomavirus
 
JC virus
 
JCV
 
M genitalium
 
microorganisms Chlamydia trachomatis
 
Mycoplasma genitalium
 
N gonorrhoeae
 
Neisseria gonorrhoeae
 
ovarian cancer
 
ovarian carcinomas
 
Ovarian tissue
 
ovarian tissues
 
polyomaviruses BK virus
 
polyomaviruses BKV
 
tissue samples