Article

Chemical synthesis in microreactors.

Department of Chemistry, University of Hull, Hull, UK.
Methods in molecular biology (Clifton, N.J.) 01/2010; 583:109-20. DOI:10.1007/978-1-60327-106-6_4 pp.109-20
Source: PubMed

ABSTRACT To develop a new generation of drugs, pharmaceutical companies need to be able to synthesise and screen novel chemicals with enhanced speed. New technology that would enable a cost neutral step change in the number of potential drug candidates would provide a distinct competitive advantage. Indeed the miniaturisation of chemical reactors offers many fundamental and practical advantages of relevance to the pharmaceutical industry, who are constantly searching for controllable, information-rich, high-throughput, environmentally friendly methods of producing products with a high degree of chemical selectivity. This chapter reviews the current and future applications of microreactors that could enhance the drug discovery process.

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Keywords

chapter reviews
 
chemical reactors
 
chemical selectivity
 
cost neutral step change
 
distinct competitive advantage
 
drug discovery process
 
fundamental
 
future applications
 
high-throughput
 
new generation
 
potential drug candidates
 
practical advantages
 
screen novel chemicals
 
synthesise
 

Paul Watts