Article

Monitoring biological interactions using perforated evanescent-field-coupled waveguide-mode nanobiosensors.

Center for Applied Near Field Optics Research (CAN-FOR), National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8562, Japan.
Nucleic Acids Symposium Series 01/2009; DOI:10.1093/nass/nrp047
Source: PubMed

ABSTRACT Evanescent-field-coupled (EFC) waveguide-mode sensors recently been shown to be suitable for detecting various biomolecules. In the present studies, we demonstrated that both nucleic acids hybridization and nucleic acids-protein interactions can be analyzed using perforated evanescent-field-coupled waveguide-mode nanobio-sensors.

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