Primary cutaneous nodular amyloidosis: case report and review of the literature.

Des Moines University College of Osteopathic Medicine and Surgery, Iowa, USA.
Cutis; cutaneous medicine for the practitioner (Impact Factor: 0.59). 08/2009; 84(2):87-92.
Source: PubMed

ABSTRACT Primary cutaneous nodular amyloidosis (PCNA) is a rare form of primary cutaneous amyloidosis. It presents as waxy yellow-red nodules that are located preferentially on the lower extremities, face, scalp, and genitals. Recognition of this condition is of particular importance, as primary systemic amyloidosis can have a similar cutaneous presentation. We report a case of PCNA in a 52-year-old woman with systemic lupus erythematosus (SLE) and Sjögren syndrome (SS). We discuss the need to evaluate for systemic disease and provide a concise review of the literature focusing on clinical presentation, disease associations, and management.