Unraveling the Secrets of Regulating Mitochondrial DNA Replication

Department of Microbiology, University of Massachusetts, Amherst, MA 01003, USA.
Molecular cell (Impact Factor: 14.02). 09/2009; 35(4):398-400. DOI: 10.1016/j.molcel.2009.08.007
Source: PubMed


In this issue, Liu et al. (2009) report that maxicircle DNA copy number in trypanosomes is regulated by proteolysis of a helicase; the complex kinetoplast DNA system yields a clear view of how mitochondrial DNA replication can be regulated.


Available from: Michele Klingbeil
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