Botanicals in skin care products.
University of Miami Cosmetic Group, Leonard M. Miller School of Medicine, Miami Heart Institute, Miami Beach, Florida 33140, USA.International journal of dermatology (Impact Factor: 1.23). 10/2009; 48(9):923-34. DOI: 10.1111/j.1365-4632.2009.04081.x
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ABSTRACT: In this study, we evaluated the anti-photoaging activity of magnolol in UV-irradiated hairless mice, and hypothesized that magnolol would prevent photoaging in these animals. The inhibitory effect of magnolol on wrinkle formation was determined by analyzing the skin replica, histologically examining the epidermal thickness, and identifying damage to the collagen fibers. The protective effects of magnolol on UVB-induced skin photoaging were examined by determining the level of MMPs and mitogen-activated protein kinases (MAPKs). Exposure to UVB radiation significantly increased skin thickness and wrinkle grade, but magnolol treatment significantly reduced the average length and depth of wrinkles, and this was correlated with the inhibition of collagen fiber loss. The magnolol-treated group had remarkably decreased activity levels of MMP-1, -9, and -13 compared to the corresponding levels in the vehicle-treated UVB-irradiated group. These results indicate that magnolol prevents skin photoaging in UVB-irradiated hairless mice.Environmental Toxicology and Pharmacology 01/2015; 39(1). DOI:10.1016/j.etap.2014.12.001 · 1.86 Impact Factor
Article: Hair Efficacy of Botanical Extracts[Show abstract] [Hide abstract]
ABSTRACT: The great increase of capillary treatments (bleaching, perming, etc.) has created an important demand for hair cosmetics designed to repair and even prevent adverse effects on the capillary structure. In this work, the effect on hair of three botanical actives is investigated. Hair was chemically damaged by bleaching and the efficacy of three botanical actives was demonstrated by evaluation of surface morphology, differential scanning calorimetry, strength/relaxation, and absorption/desorption properties. Bleaching treatments have been demonstrated to modify the hair properties producing an increase in the fiber permeability and detrimental effects on the mechanical properties. Application of the botanical extracts to pretreated hair has improved the mechanical properties, giving rise to a reduction of the fibres' permeability, coating them and increasing the crystalline material of the fibers. Treatments with botanical actives based on either proteins and peptides, sulfated polysaccharides or a combination of polysaccharides could be used to protect and repair the hair fibers. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013Journal of Applied Polymer Science 04/2013; 128(1). DOI:10.1002/app.38244 · 1.64 Impact Factor
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