Mucinous Adenocarcinoma of the Prostate: MRI and MR Spectroscopy Features

Department of Radiology, University of California, San Francisco, 505 Parnassus Ave., M-372, Box 0628, San Francisco, CA 94143-0628, USA.
American Journal of Roentgenology (Impact Factor: 2.73). 10/2009; 193(3):W238-43. DOI: 10.2214/AJR.08.1495
Source: PubMed


OBJECTIVE: The purpose of this study was to investigate the MRI and MR spectroscopy features of mucinous adenocarcinoma of the prostate. CONCLUSION: MRI and MR spectroscopy do not appear to provide the ability to reliably detect the lakes of extracellular mucin seen in mucinous adenocarcinoma of the prostate.

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Available from: Antonio C Westphalen, Sep 30, 2014
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    • "T1-weighted images illustrate prostate as homogeneous low signal intensity organ in which zonal anatomy and prostate cancer distinguishing is very difficult. T1-weighted is a useful image in detecting Post biopsy hemorrhage in prostate cancer (appears as high T1 signal intensity areas within the homogeneous prostate) and assess lymph nodes and osseous structures in pelvis (29-30). T2-weighted high resolution images are the mainstay in prostate cancer detection. "
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    ABSTRACT: Imaging studies play an important role in detection and management of prostate cancer and MRI especially with the use of endorectal coil because of high contrast resolution is recognized as the best imaging modality in evaluation of prostate cancer. Multiparametric MR study including T1 and T2 weighted images, diffusion weighted images, dynamic contrast study and MR spectroscopy is useful for detection and local staging of prostate cancer as well as posts treatment evaluation of patients either after surgery or radiation therapy for detection of local recurrence.
    12/2013; 15(12):e16620. DOI:10.5812/ircmj.16620
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    ABSTRACT: OBJECTIVE: This review is a primer on the technical aspects of performing a high-quality MRI and MR spectroscopic imaging examination of the prostate. CONCLUSION: MRI and MR spectroscopic imaging are useful tools in the localization, staging, and functional assessment of prostate cancer. Performing a high-quality MR spectroscopic examination requires understanding of the technical aspects and limitations of spectral acquisition, postprocessing techniques, and spectral evaluation.
    American Journal of Roentgenology 06/2010; 194(6):1414-26. DOI:10.2214/AJR.10.4312 · 2.73 Impact Factor
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    ABSTRACT: Prostate cancer is the most frequently diagnosed cancer in males and the second leading cause of cancer-related death in men. Assessment of prostate cancer can be divided into detection, localization, and staging; accurate assessment is a prerequisite for optimal clinical management and therapy selection. Magnetic resonance (MR) imaging has been shown to be of particular help in localization and staging of prostate cancer. Traditional prostate MR imaging has been based on morphologic imaging with standard T1-weighted and T2-weighted sequences, which has limited accuracy. Recent advances include additional functional and physiologic MR imaging techniques (diffusion-weighted imaging, MR spectroscopy, and perfusion imaging), which allow extension of the obtainable information beyond anatomic assessment. Multiparametric MR imaging provides the highest accuracy in diagnosis and staging of prostate cancer. In addition, improvements in MR imaging hardware and software (3-T vs 1.5-T imaging) continue to improve spatial and temporal resolution and the signal-to-noise ratio of MR imaging examinations. Another recent advancement in the field is MR imaging guidance for targeted prostate biopsy, which is an alternative to the current standard of transrectal ultrasonography-guided systematic biopsy.
    Radiographics 05/2011; 31(3):677-703. DOI:10.1148/rg.313105139 · 2.60 Impact Factor
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