Article

Combination of autologous fascia lata and fat injection into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis.

Department of Otolaryngology-Head and Neck Surgery, Jinling Hospital, Clinical Medical College of Nanjing University, 305 E Zhongshan Road, Nanjing, China.
Archives of otolaryngology--head & neck surgery (impact factor: 1.92). 09/2009; 135(8):759-63. DOI:10.1001/archoto.2009.91 pp.759-63
Source: PubMed

ABSTRACT To apply the technique of injection of a combination of autologous fascia lata and fat into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis and to evaluate the therapeutic effect in 12 patients who underwent the procedure.
Retrospective analysis of 12 patients.
Academic research.
A mixture of autologous fascia lata and fat was injected into the thyroarytenoid muscle of the paralyzed vocal fold in 12 patients.
Videolaryngostroboscopy was performed to observe the changes to the vocal fold. The patients' phonatory function before and after surgery was assessed by computerized acoustic analysis and by blinded perceptual evaluation.
Videolaryngostroboscopy demonstrated that the paralyzed vocal folds in these patients were pushed medially after the procedure. Statistically significant improvements were found in the perturbation measurements (jitter and shimmer), harmonics to noise ratio, and maximum phonation time. Ratings by a panel of voice experts also showed each voice to be statistically significantly improved after the procedure. No complications were noted.
A combination of autologous fascia lata and fat injected into the vocal fold for unilateral vocal fold paralysis is a safe and effective therapy.

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Keywords

12 patients
 
autologous fascia lata
 
computerized acoustic analysis
 
effective therapy
 
medially
 
noise ratio
 
paralyzed vocal
 
paralyzed vocal folds
 
patients' phonatory function
 
perceptual evaluation
 
perturbation measurements
 
Ratings
 
Retrospective analysis
 
shimmer
 
Statistically significant improvements
 
therapeutic effect
 
thyroarytenoid muscle
 
unilateral vocal
 
vocal
 

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