Neurosurgery for obsessive-compulsive disorder: Contemporary approaches

School of Psychology, Deakin University, Burwood, Victoria, Australia.
Journal of Clinical Neuroscience (Impact Factor: 1.38). 09/2009; 17(1):1-5. DOI: 10.1016/j.jocn.2009.02.043
Source: PubMed


Surgery for psychiatric disorders has a controversial history. Traditionally, procedures were undertaken to physically disconnect or destroy certain areas of the brain thought to constitute critical components of the limbic pathways. The relatively recent advent of the much safer and non-destructive technique known as deep brain stimulation has coincided with a resurgence in interest in psychosurgery. Contemporary approaches to the surgical management of obsessive-compulsive disorder are discussed, together with our current understanding of its pathophysiology.

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    • "When pathologies are in the close proximity of functional cortices or neural tracts, the use of functional neurosurgery techniques may be seen as the only standard approach (Bauer, Martin et al. 2014). NMD is increasingly applied in treating refractory and medication-resistant major depression and obsessive compulsive disorder (OCD) (Greenberg, Price et al. 2003, Bear, Fitzgerald et al. 2010). Nevertheless, in case a resistant patient has failed to respond to all previously tried medications or electroconvulsive therapy (ECT), it is possible that further physical treatments such as surgery and deep brain stimulations (DBS) are similarly inappropriate (Greenberg, Price et al. 2003). "
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