Congenital heart block associated with Sjögren syndrome: Case report

Cancer Sciences Division, School of Medicine, University of Southampton, Southampton SO16 6YD, UK.
International Archives of Medicine (Impact Factor: 1.08). 08/2009; 2(1):21. DOI: 10.1186/1755-7682-2-21
Source: PubMed


Congenital heart block is a rare complication of pregnancy associated with Sjögren Syndrome that may result in the death of the foetus or infant, or the need for pacing in the newborn or at a later stage.
The case is presented of a 64-year-old patient with primary Sjögren Syndrome and a history of having given birth to two sons with congenital heart block, both of whom required pacing several years later.
The literature relating to this association is discussed including the suggested mechanism, long-term outcome of mothers of children with congenital heart block and preventive treatment strategies.

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    • "Gestational impairments are important factors to be investigated [1,2], since it affects children development [3-5]. The hydatidiform mole (HM) is a variant of gestational trophoblastic disease, a generic term that brings together different conditions of proliferation of trophoblastic epithelium, with abnormal functioning tissue producing human chorionic gonadotropin (hCG) [6]. "
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