Stability of blood analytes after storage in BD SST (TM) tubes for 12 mo
ABSTRACT Objectives: We studied the stability of 33 analytes related to clinical chemistry, bone, and vitamin metabolism, after storage in serum separator tubes (SST (TM)). Design and methods: Blood was collected from 6 subjects using SST tubes. Some serum remained in the tube in contact with the barrier gel and was stored at -80 degrees C for 12 mo. Results: Clinically significant changes Occurred only in 1,25-dihydroxyvitamin D and retinol-binding protein. Conclusions: Freezing SST tubes before sample analysis is a viable option for some analytes.
Clinical Chemistry and Laboratory Medicine 09/2014; 53(3). DOI:10.1515/cclm-2014-0543 · 2.96 Impact Factor
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ABSTRACT: Abstract Context: In epidemiological research, it is very important to test the stability of biomarkers as function of both storage time and temperature. Objective: In this study, the stability of biomarkers of the iron status was tested up to 1 year of storage. Materials and methods: The biomarkers include total iron, unsaturated iron binding capacity, ferritin, transferrin, soluble transferrin receptor, ceruloplasmin and haptoglobin. Results: The concentrations of all biomarkers tested remain constant upon storage at -20, -70 and -196 °C. Conclusion: All biomarkers of the iron status were stable at the temperatures tested for 1 year.Biomarkers 04/2013; DOI:10.3109/1354750X.2013.781223 · 2.52 Impact Factor
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