Article

Evaluation of Antibacterial Effects of Shiraz Oregano Essence (Zataria Multiflora Boiss) on Salmonella typhi and Comparing with Antibiotics

Research Journal of Biological Sciences 01/2007;
Source: DOAJ

ABSTRACT According to increased bacterial resistance to common antibiotics, tendency toward using herbal drugs is increasing. Many researches have been executed about antibacterial and preservative effects of herbal essence like essences extracted from plants of Lamiaceae family (like Shiraz oregano herb). In this study, antibacterial effects of Shiraz oregano on Salmonella typhi Murium that is one of main causes of food poisoning in human, is evaluating. To provide essence 50 g of dried ground leaf of plant beside 700 mL of distilled water were poured into flask and with 1 mL min-1 velocity distillation the essence was extracted. Determination of microbial sensitivity was performed in the Kirby Bauer method. Minimal Inhibitory Condensation (MIC) and minimal bactericidal condensation for Shiraz oregano plant were 312.5 μg mL-1 and 652 μg mL-1, respectively. The most sensitivity of Salmonella typhi Murium was to Trimethoprim sulfamethoxazole (TMP-SMX) and Chloramphenicole and it was severely resistant to other antibiotics. Activity of Shiraz oregano essence against Salmonella typhi Murium was more than Tetracyclin`s activity, but in comparison with Trimethoprim sulfamethoxazole (TMP-SMX) and Chloramphenicole is lower. According to obtained results and limitations of increasingly usage of chemical antimicrobial substances there is a need to replacement of these substances with natural and herbal essences.

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