Article

Processing speed impairment in schizophrenia is mediated by white matter integrity.

Psychological Medicine (Impact Factor: 5.43). 05/2014; DOI: 10.1017/S0033291714001111
Source: PubMed

ABSTRACT Processing speed predicts functional outcome and is a potential endophenotype for schizophrenia. Establishing the neural basis of processing speed impairment may inform the treatment and etiology of schizophrenia. Neuroimaging investigations in healthy subjects have linked processing speed to brain anatomical connectivity. However, the relationship between processing speed impairment and white matter (WM) integrity in schizophrenia is unclear.

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