Article

Choosing a control group in effectiveness trials of behavioral drug abuse treatments

Maryhaven Research Institute, Maryhaven, Columbus, OH 43207, USA.
Journal of substance abuse treatment (Impact Factor: 2.9). 07/2009; 37(4):388-97. DOI: 10.1016/j.jsat.2009.05.004
Source: PubMed

ABSTRACT Effectiveness trials are an important step in the scientific process of developing and evaluating behavioral treatments. The focus on effectiveness research presents a different set of requirements on the research design when compared with efficacy studies. The choice of a control condition has many implications for a clinical trial's internal and external validity. The purpose of this article was to provide a discussion of the issues involved in choosing a control group for effectiveness trials of behavioral interventions in substance abuse treatment. The authors provide a description of four trial designs and a discussion of the advantages and disadvantages of each.

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Available from: Daniel J Feaster, Aug 01, 2015
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    • "Note that Design 2 in the original conceptualization (Brigham, Feaster, Wakim, and Dempsey, 2009) has been subdivided into Design 2a and Design 2b, depending on whether the new intervention is an add-on to TAU, or substitutes for some existing component of TAU. "
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