Developing a Research Agenda for The American Society of Colon and Rectal Surgeons: Results of a Delphi Approach
ABSTRACT By use of a systematic approach, the aim of this project was to survey a group of colorectal specialists and reach a consensus on the research questions of highest importance in terms of clinical care.
A modified Delphi process was performed. In Round 1 research questions were solicited from members of The American Society of Colon and Rectal Surgeons. A review group categorized the results, combined similar questions, and presented them to The American Society of Colon and Rectal Surgeons membership in Round 2 for prioritizing according to importance. In Round 3 the 50 questions with the highest scores in Round 2 were reranked by The American Society of Colon and Rectal Surgeons membership to produce the 20 highest-priority research questions.
A total of 203 respondents in Round 1 submitted 746 questions. The review team reduced these to 105 individual questions encompassing 21 topics in colorectal surgical practice. In Rounds 2 and 3, 399 and 360 respondents, respectively, prioritized the questions presented. The final 20 items included 14 questions related to colorectal cancer, and 6 were on benign disease topics.
The research agenda produced by this study reflects the clinical issues of greatest importance to colorectal surgeons. The results are of potential benefit to researchers, funding organizations, medical journals, and ultimately, patients.
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ABSTRACT: Mean diffusion of 6-methyl-16-methylene-17α-acetoxypregna-4, 6-diene-3, 20-dione through dimethylpolysiloxane membrane into water was 140 μg/24 hrs/100 mm2/0.1 mm; (dl)-13β-ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one diffused with a rate of 73 μg/24 hrs/100 mm2/0.1 mm. When plasma instead of water was used for incubation, the diffusion rates were increased by the following factors: 2.4 times for 19-norpregn-4-ene-3, 20-dione; 1.5 times for 6-methyl-17α-acetoxypregna-4, 6-diene-3, 20-dione, and 4.7 times for (dl)-13β-ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one. Measurements of diffusion through porous glass discs, and of solubility in different solvents indicated that the steroid molecules diffuse through the dimethylpolysiloxane in a non-solvated form.Steroids 01/1968; 12(4):517-524. DOI:10.1016/S0039-128X(68)80115-1 · 2.72 Impact Factor
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ABSTRACT: To describe systems for capturing and optimising collective knowledge and insight in areas of complexity and uncertainty in surgical oncology, with particular reference to the Delphi process and related systems. Internet search engines (Google, Google Scholar) and four databases (SCOPUS, PubMed, Medline and Embase) were searched to find English language articles on the use of The Delphi Process and related systems in surgical oncology, using a variety of search terms. There are a number of established systems for co-opting group knowledge and facilitating collective decision-making. These find applications in commerce, industry, government and defence. They have also been applied to problems in surgical oncology, for example using the Delphi process to optimise the management of colorectal cancers and metastases. Collective decision making tools find practical applications in the allocation of resources and in clinical decision making in fields of surgical oncology practice where there is a wide range of evidence and expert opinion. Such methodologies set new standards for the collating of professional expertise and for the writing of "best clinical practice" guidelines in the cancer subspecialities.European journal of surgical oncology: the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 03/2010; 36(3):230-6. DOI:10.1016/j.ejso.2010.01.002 · 2.89 Impact Factor
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ABSTRACT: Clinical research is an important part of an academic surgery practice. To be successful, it is important to understand the multiple regularity committees and organizations that impact research. The author briefly reviews these groups and provides guidance on how to initiate and conduct research.06/2011; 24(2):100-5. DOI:10.1055/s-0031-1278405