Article

Imaging cerebral haemorrhage with magnetic induction tomography: numerical modelling.

School of Medicine, Swansea University, Swansea, SA2 8PP, UK.
Physiological Measurement (impact factor: 1.68). 07/2009; 30(6):S187-200. DOI:10.1088/0967-3334/30/6/S13 pp.S187-200
Source: PubMed

ABSTRACT Magnetic induction tomography (MIT) is a new electromagnetic imaging modality which has the potential to image changes in the electrical conductivity of the brain due to different pathologies. In this study the feasibility of detecting haemorrhagic cerebral stroke with a 16-channel MIT system operating at 10 MHz was investigated. The finite-element method combined with a realistic, multi-layer, head model comprising 12 different tissues, was used for the simulations in the commercial FE package, Comsol Multiphysics. The eddy-current problem was solved and the MIT signals computed for strokes of different volumes occurring at different locations in the brain. The results revealed that a large, peripheral stroke (volume 49 cm(3)) produced phase changes that would be detectable with our currently achievable instrumentation phase noise level (17 m degrees ) in 70 (27%) of the 256 exciter/sensor channel combinations. However, reconstructed images showed that a lower noise level than this, of 1 m degrees , was necessary to obtain good visualization of the strokes. The simulated MIT measurements were compared with those from an independent transmission-line-matrix model in order to give confidence in the results.

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Keywords

12 different tissues
 
16-channel MIT system
 
256 exciter/sensor channel combinations
 
commercial FE package
 
detecting haemorrhagic cerebral stroke
 
different locations
 
different pathologies
 
different volumes
 
eddy-current problem
 
feasibility
 
good visualization
 
image changes
 
independent transmission-line-matrix model
 
lower noise level
 
Magnetic induction tomography
 
MIT signals computed
 
new electromagnetic imaging modality
 
phase changes
 
reconstructed images
 
simulated MIT measurements