Article

High-risk pregnancy in rhesus monkeys (Macaca mulatta): a case of ectopic, abdominal pregnancy with birth of a live, term infant, and a case of gestational diabetes complicated by pre-eclampsia.

Research Animal Resources Center, University of Wisconsin-Madison, Madison, WI, USA.
Journal of Medical Primatology (impact factor: 1.3). 04/2009; 38(4):252-6. DOI:10.1111/j.1600-0684.2009.00349.x
Source: PubMed

ABSTRACT Cases of abdominal pregnancy, in the form of intra-abdominal mummified fetuses, have been described in nonhuman primates. Gestational diabetes and pre-eclampsia are common pregnancy complications in women.
Two timed-bred rhesus monkeys had high-risk pregnancies, an abdominal pregnancy with delivery of a live term infant, and a case of gestational diabetes that later developed pre-eclampsia.
The monkey that had abdominal pregnancy later died from septic peritonitis. The monkey had a colonic adenocarcinoma that may have allowed leakage of intestinal contents into the abdomen. Her infant was fostered to another female and survived. The monkey with gestational diabetes and pre-eclampsia was treated with a regimen similar to that used in women, and a live infant was delivered at day 157 of gestation by Caesarian section.
These cases underscore the value of timed-breeding and the similarities between pregnancy complications in women and in nonhuman primates.

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Keywords

abdominal pregnancy
 
Caesarian section
 
Cases
 
colonic adenocarcinoma
 
developed pre-eclampsia
 
Gestational diabetes
 
intestinal contents
 
intra-abdominal mummified fetuses
 
leakage
 
live infant
 
live term infant
 
pre-eclampsia
 
pregnancy complications
 
septic peritonitis
 
timed-bred rhesus monkeys
 
women