Article

Verbesinosides A-F, 15,27-cyclooleanane saponins from the American native plant Verbesina virginica.

Wen-Hui Xu, Melissa R Jacob, Ameeta K Agarwal, Alice M Clark, Zong-Suo Liang, Xing-Cong Li

National Center for Natural Products Research, Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, Mississippi 38677, USA.

Journal of Natural Products (impact factor: 3.13). 06/2009; 72(6):1022-7. DOI:10.1021/np900180y pp.1022-7

Source: PubMed

ABSTRACT Verbesinosides A-F (1-6), six new 15,27-cyclooleanane-type triterpenoid saponins carrying different aromatic acyl moieties on the aglycon, were isolated from the leaves and flowers of Verbesina virginica. Their structures were established by interpretation of spectroscopic data and chemical methods. The representative major saponin, verbesinoside A (1), has the structure 21-trimethoxybenzoyl 15alpha,27-cycloolean-12-en-3beta,21beta-diol-28-oic acid 3-O-beta-D-xylopyranosyl(1-->4)-beta-D-xylopyranosyl(1-->2)-beta-D-glucopyranoside. This is the first report of triterpenoid saponins possessing the unique 15,27-cyclooleanane skeleton. The anisotropic effects of the aromatic acyl moieties on the triterpenoid skeleton are discussed.

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Article: 9,19-cyclolanostane derivatives from the roots of Actaea pachypoda.

Zulfiqar Ali, Shabana I Khan, Rahul S Pawar, Daneel Ferreira, Ikhlas A Khan

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ABSTRACT: Phytochemical investigation of the chemical constituents of the roots of Actaea pachypoda afforded 12 9,19-cyclolanostane type triterpenoids, including the new 7,8-dihydroactaeaepoxide 3-O-beta-d-xylopyranoside (1), 12-deacetoxyactaeaepoxide 3-O-beta-d-xylopyranoside (2), and 12beta-acetoxycimigenol (3). Their structures were determined by spectroscopic and chemical methods.

Journal of Natural Products 02/2007; 70(1):107-10. · 3.13 Impact Factor
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Article: Sclerotiamide: a new member of the paraherquamide class with potent antiinsectan activity from the sclerotia of Aspergillus sclerotiorum.

A C Whyte, J B Gloer, D T Wicklow, P F Dowdw

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ABSTRACT: Sclerotiamide (1), a new fungal natural product related to the paraherquamides, was isolated by bioassay-guided fractionation of antiinsectan organic extracts from the sclerotia of Aspergillus sclerotiorum (NRRL 5167). The structure was determined primarily through 1H-NMR, 13C-NMR, HMQC, and HMBC experiments. Sclerotiamide causes significant mortality and unusual physiological effects in dietary assays against the corn earworm Helicoverpa zea.

Journal of Natural Products 12/1996; 59(11):1093-5. · 3.13 Impact Factor

Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.

Keywords

anisotropic effects

aromatic acyl moieties

chemical methods

different aromatic acyl moieties

new 15,27-cyclooleanane-type triterpenoid saponins

triterpenoid saponins

triterpenoid skeleton

unique 15,27-cyclooleanane skeleton

verbesinoside

Verbesinosides A-F

Verbesinosides A-F, 15,27-cyclooleanane saponins from the American native plant Verbesina virginica.

Article: 9,19-cyclolanostane derivatives from the roots of Actaea pachypoda.

Article: Sclerotiamide: a new member of the paraherquamide class with potent antiinsectan activity from the sclerotia of Aspergillus sclerotiorum.

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Verbesinosides A-F, 15,27-cyclooleanane saponins from the American native plant Verbesina virginica.

Article: 9,19-cyclolanostane derivatives from the roots of Actaea pachypoda.

Article: Sclerotiamide: a new member of the paraherquamide class with potent antiinsectan activity from the sclerotia of Aspergillus sclerotiorum.

View other sources

Hide other sources

View other sources

Hide other sources

Keywords

Similar Publications

Isolation and characterization of new minor triterpenoid saponins from the buds of Lonicera macranthoides.

A new triterpenoid saponin from Sanguisorba officinalis.

Oleanane-type triterpenoid saponins from the roots of Pulsatilla koreana and their apoptosis-inducing effects on HL-60 human promyelocytic leukemia cells.

Melissa Jacob

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