A recent attribution of vegetables to human health stems from their effect on the gasotransmitter nitric oxide (NO). This commentary proposes that a major reason for this attribution is that vegetables are rich in nitrates. Recent research has shown that nitrites and nitrates are not only inert end-products of NO oxidation. In addition, they can be recycled back to bioactive NO and this pathway is an important alternative to the classical l-arginine-NO-synthase pathway. Various chronic ailments, e.g., diabetes, obesity, high blood pressure, are symptomatic of NO bioavailability. Because NO deficiency is metabolically complex, natural nitrate-rich nutrients, like green leafy vegetables, can improve these chronic ailments via the alternative nitrate-NO pathway. This commentary implies an added value for vegetables in enhancing health such as cardiac health and in lowering the risks of maladies such as diabetes.
"Entire report not peer-reviewed Rosen (2008b) Correction of the errors and omissions in Benbrook and others (2008) indicates that there is essentially no nutritional difference between organic and conventional foods Not peer-reviewed either Dangour and others (2009) No difference in nutrients and no difference in putative health effects Methods and results peer-reviewed review (Hord and others 2009) concludes that " the data on nitrate and nitrite contents of vegetables and fruit bolster the strength of existing evidence to recommend their consumption for health benefits " and that plant origin nitrates and nitrites " play essential physiologic roles supporting cardiovascular health and gastrointestinal immune function. " Finally, an article published recently in Medical Hypotheses suggested that ingestion of high nitratecontaining fruits and vegetables such as pomegranates, lettuce, spinach, and beets might be useful in lowering obesity, diabetes, hypertension, and coronary artery disease (Ralt 2009). "
[Show abstract][Hide abstract] ABSTRACT: Health-conscious consumers have an interest in knowing if the extra money they spend on organic food is justified. The organic food industry, therefore, has a large financial interest in convincing the public that the food they sell is healthier, tastier, and better for the environment. One area that the industry has concentrated on is the supposed nutritional superiority of their product. The importance of this area to the organic food industry can be seen by the vehemence in which it has attacked and tried to discredit a recent, widely circulated report submitted to the British government that found no scientific evidence for claims that organic food is nutritionally superior to conventional food. Two nongovernment organizations, the Soil Assn. in the United Kingdom and the Organic Center in the United States have been heavily involved in the promotion of organic food. Both of these organizations exert a great deal of influence with the media, and hence with consumers, in both countries. An examination of some of their actions will be included in this article.
Comprehensive Reviews in Food Science and Food Safety 04/2010; 9(3):270 - 277. DOI:10.1111/j.1541-4337.2010.00108.x · 4.18 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Microcontainers with embedded superparamagnetic nanoparticles can be changed into bubble microreactors upon treatment with an alternating magnetic field, which acts as a remote trigger for the release of encapsulated material. Exchange of an arginine solution inside and H2O2 solution outside the microcontainers generates NO gas. The microstructure combines ultrasound diagnostic and NO therapeutic functionalities.
Small 06/2010; 6(12):1300-5. DOI:10.1002/smll.201000173 · 8.37 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: An ionic liquid dispersive liquid-liquid microextraction high-performance liquid chromatography (IL-DLLME-HPLC) method for effective enrichment and determination of nitrite ion in water and biological samples was developed. The method was based on the reaction of nitrite ion with p-nitroaniline in the presence of diphenylamine in acid media and IL-DLLME of azo product. The optimization of reaction and extraction conditions, such as kind and concentration of acid, reaction time, volume of reaction solvent, temperature, kind of extraction and dispersive solvent, volume of extraction and dispersive solvent, addition of salt, extraction and centrifugal time were studied. Under the optimal conditions, 1-octyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]imide IL-DLLME procedure provided high enrichment factor of 430 and good extraction recovery of 91.7% for nitrite ion. The linearity was observed in the range of 0.4-500.0 μg L⁻¹ with good correlation coefficient (r²=0.9996). The relative standard deviations (RSDs) for five replicate measurements varied between 1.5% and 4.8%. The limit of detection of the method (S/N=3) was 0.05 μg L⁻¹. The interference effect of some anions and cations was also tested. The developed method allowed achieving an excellent enrichment factor, yielding a lower LOD in comparison with other methods. Moreover, the proposed method was able to analyze nitrite ion in water and biological samples with satisfactory recovery ranged from 96.5% to 107.3%.
Journal of Chromatography A 06/2011; 1218(23):3595-600. DOI:10.1016/j.chroma.2011.04.014 · 4.17 Impact Factor
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.