Article

Quality of life after oral and oropharyngeal reconstruction with a radial forearm free flap: prospective study.

Département de Chirurgie, Institut Universitaire de la Face et du Cou, Centre Antoine-Lacassagne, 33 avenue de Valombrose, Nice 06189, France.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale (impact factor: 0.71). 07/2009; 38(3):401-8. pp.401-8
Source: PubMed

ABSTRACT To evaluate quality of life (QOL) after radial forearm free flap (RFFF) reconstruction of the oral cavity and oropharynx in head and neck cancer patients.
Prospective study.
Academic, tertiary referral centre.
Between January 2004 and May 2005, 47 patients underwent immediate RFFF reconstruction of the oral cavity and oropharynx following ablative surgery for a previously untreated head and neck cancer and were initially included in this study. The European Organization for Research and Treatment of Cancer (EORTC) Core Quality of Life Questionnaire and the EORTC Head and Neck Cancer Quality of Life Questionnaire were completed before surgery and at 6 and 12 months thereafter.
QOL scores obtained at the three assessment dates. Predictive factors of QOL scores at 6 months researched among the following: age, gender, comorbidity, radiotherapy, tumour stage, and tumour site.
Global QOL remained stable over time. Social and role functioning scores deteriorated significantly after treatment. Social eating and speech difficulties, trismus, and salivary problems increased significantly in the postoperative period and were among the main complaints of our patients.
Despite some functional impairment, global QOL was preserved after RFFF reconstruction following extensive ablative surgery in patients with oral and oropharyngeal cancer.

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Keywords

12 months
 
47 patients
 
6 months researched
 
EORTC Head
 
extensive ablative surgery
 
Global QOL
 
immediate RFFF reconstruction
 
neck cancer
 
neck cancer patients
 
Neck Cancer Quality
 
oral cavity
 
oropharyngeal cancer
 
postoperative period
 
Prospective study
 
radial forearm free flap
 
RFFF reconstruction
 
tertiary referral centre
 
three assessment dates
 
tumour site
 
untreated head