Sarcomatoid carcinoma of the penis: Clinicopathologic features
Sarcomatoid carcinomas are biphasic tumors, which can occur at any site in the human body. Very few cases have been reported in the literature as arising from the penis. A few studies consider these tumors as a variant of squamous cell carcinoma or a metaplastic differentiation of the mesenchyme. Their clinical behavior is aggressive with both blood borne and lymphatic metastases. Treatment is by surgical excision, and dissected lymph nodes have shown both epithelial and sarcomatous components. We report a 50-year-old gentleman, with a sarcomatoid carcinoma of the penis, which was confirmed immunopathologically. The rarity of this entity makes it a clinicopathologic curiosity.
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ABSTRACT: A 64-year-old man presented with gross hematuria. Physical examination showed a mass under the phimotic foreskin. Circumcision revealed a 2cm polypoid tumor on the inner layer of prepuce. Tumor resection was performed and pathological diagnosis was carcinosarcoma which was composed of squamous cell carcinoma and spindle cell sarcoma. Biopsy of the scar lesions revealed residual squamous cell carcinoma and computed tomographic scan revealed swollen inguinal lymph nodes. Partial penectomy and lymph node biopsy were performed. Pathological examination revealed residual squamous cell carcinoma and no lymph node metastasis. There was no recurrence for one year. We report this very rare case of carcinosarcoma of the penis.Hinyokika kiyo. Acta urologica Japonica 06/2011; 57(6):345-8.
Article: Penile cancer: An update[Show abstract] [Hide abstract]
ABSTRACT: Penile cancer is a rare disease with devastating physical and psychological effects on patients. The aim of this review is to update specialist nurses regarding the epidemiology, aetiology and management.International Journal of Urological Nursing 10/2011; 5(3):97 - 106. DOI:10.1111/j.1749-771X.2011.01126.x · 0.19 Impact Factor
- Cytopathology 06/2014; 26(4). DOI:10.1111/cyt.12164 · 1.48 Impact Factor
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