A Randomized, Controlled Trial to Increase Discussion of Breast Cancer in Primary Care

Cancer Epidemiology Biomarkers & Prevention (Impact Factor: 4.13). 04/2014; 23(7). DOI: 10.1158/1055-9965.EPI-13-1380
Source: PubMed


Background: Assessment and discussion of individual risk for breast cancer within the primary care setting are crucial to discussion of risk reduction and timely referral. Methods: We conducted a randomized controlled trial of a multiethnic, multilingual sample of women aged 40-74 years from two primary care practices (one academic, one safety-net) to test a breast cancer risk assessment and education intervention. Patients were randomly assigned to control or intervention group. All patients completed a baseline telephone survey and risk assessment (via telephone for controls, via tablet computer in clinic waiting room prior to visit for intervention). Intervention (BreastCARE) patients and their physicians received an individualized risk report to discuss during the visit. One-week follow-up telephone surveys with all patients assessed patient-physician discussion of: family cancer history, personal breast cancer risk, high-risk clinics, and genetic counseling/testing. Results: 655 control and 580 intervention women completed the risk assessment and follow-up interview; 25% were high-risk by family history, Gail, or Breast Cancer Surveillance Consortium risk models. BreastCARE increased discussions of family cancer history (OR=1.54, 95% CI=1.25-1.91), personal breast cancer risk (OR=4.15, 3.02-5.70), high-risk clinics (OR=3.84, 2.13-6.95), and genetic counseling/testing (OR=2.22, 1.34-3.68). Among high-risk women, all intervention effects were stronger. Conclusions: An intervention combining an easy-to-use, quick risk assessment tool with patient-centered risk reports at the point of care can successfully promote discussion of breast cancer risk reduction between patients and primary care physicians, particularly for high-risk women. Impact: Next steps include scaling and dissemination of BreastCARE with integration into electronic medical record systems.

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Available from: Eliseo J Pérez-Stable, Oct 13, 2014